Mechanism of Heat Shock Protein 90 as Molecular Chaperone in Glucocorticoid Receptor Signal Pathway 热休克蛋白90在糖皮质激素受体信号通路中的分子伴侣作用
Objective To reveal the proteomic change of molecular chaperone in skin cell induced by UV radiation. 目的初步探讨紫外线辐射所致皮肤细胞分子伴侣蛋白质组整体变化规律。
Influencing factors in the refolding process of artificial molecular chaperone assisting chicken IL-18 recombination protein 人工分子伴侣系统辅助鸡IL-18重组蛋白复性过程中研究的影响因素
Study of DsbA-DsbA~ ( mut) as Molecular Chaperone in Prokaryotic Expression System DsbA-DsbA~(mut)融合蛋白作为分子伴侣在原核表达系统中的作用研究
Over the last decade focused on the study of protein folding, opened up a new direction for molecular chaperone and folding enzymes in China. 近十几年来集中在蛋白质折叠研究,在国内开辟了分子伴侣和折叠酶研究的新方向。
This paper discussed the classification, function, mechanism, current research progress and the application prospect of the molecular chaperone. 本文综述了分子伴侣的分类、功能、作用机理、研究现状及应用前景。
The heat shock protein Hsp90 is a molecular chaperone that binds to various denatured or unfolded client proteins and helps shuttle them into the proteasome for recycling. 热休克蛋白90作为环境相关性分子伴侣中的一员,可以使细胞信号转导蛋白的构象成熟、功能稳定。
The term "molecular chaperone" was originally used to describe a class of biomolecules, which mediate interactions between nuclear acids and proteins in the nucleus. 分子伴侣一词最初是指一类在细胞核内介导蛋白和核酸相互作用的生物分子。
Co-expression of protein of M. tuberculosis with molecular chaperone 应用分子伴侣共表达系统表达结核分枝杆菌编码蛋白
Purpose: To evaluate the molecular chaperone function of α-crystallin in age-related cataract. 研究年龄相关性白内障α-晶状体蛋白的分子伴侣功能。
Progress on Molecular Chaperone and Its Role in Protein Folding 分子伴侣及其在蛋白质折叠中的作用研究进展
Character of α-Crystallin Molecular Chaperone Activity in Selenite Cataract 硒性白内障α-晶体蛋白的分子伴侣特性
Kinetics of lysozyme refolding facilitated by molecular chaperone GroEL 分子伴侣GroEL促进溶菌酶复性动力学
But they do hardly form complexes with a typical molecular chaperone at those unfolded, hydrophobic surfaces exposed state. 但是,在蛋白处于上述天然结构丧失、疏水表面暴露的状态时,其不与典型的分子伴侣蛋白形成复合物。
The ER molecular chaperone machinery and the associated quality control mechanisms not only optimize folding and assembly of newly synthesized secretory proteins but also dispose of defective ones. 分子伴侣和质量控制不仅能优化新合成蛋白的折叠和组装,而且去除了有折叠缺陷的蛋白。
Phylogeny of molecular chaperone 60 proteins 分子伴娘60类群的系统发育学分析
Modification of α-crystallin and reduction of molecular chaperone activity by glycation 糖基化对α-晶状体蛋白的修饰和分子伴侣活性的降低
Cpn 10 is a subclass of chaperonins, which is a protein family in molecular chaperone. Chaperonins是分子伴侣中的一个蛋白家族,Cpn10属于其中的一个亚类。
Effect of infrasound on molecular chaperone activity of α-crystallin 次声对α-晶体蛋白分子伴侣活性的影响
Effects of fructose 6-phosphate and ribose on molecular chaperone activity of α-crystallin 6-磷酸果糖和核糖对α-晶状体蛋白分子伴侣活性的作用
Heat shock protein ( HSP) comprises of a group of highly conserved and stress-related proteins with many important physiological and pathological roles such as cellular homeostasis, molecular chaperone, tumor markers, molecular adjuvant and so on. 热休克蛋白是一组高度保守的、与应激相关的蛋白质,具有许多重要的生理和病理作用,如:细胞自稳、分子伴侣、肿瘤标志物和分子佐剂等。
Change of Endoplasmic Reticulum Molecular Chaperone in the Process of Escherichia Coli Invasion to Human Brain Microvascular Endothelial Cells 内质网分子伴侣在大肠杆菌对人脑微血管内皮细胞侵袭过程中的变化
The function and application of molecular chaperone 分子伴侣的功能和应用
Renaturation yield of recombinant protein have been improved by using some additives, such as molecular chaperone, small molecules that interfere with intermolecular interactions responsible for aggregation. 分子伴侣、低分子量添加物等在复性过程中的应用及新的复性方法的建立都大大提高了重组蛋白质复性产率表达的rPA占菌体总蛋白的40%,以包涵体形式存在。
These results indicated that there were differences among glutathione synthetase, molecular chaperone and antioxidant enzyme in heavy metal resistance mechanisms, and glutathione synthetase had more obvious advantages in exercising the functions of heavy metal bioremediation. 这说明谷胱甘肽合成相关酶、分子伴侣和抗氧化酶在重金属抗性机制方面有所不同,并且在行使重金属污染生物修复功能方面,谷胱甘肽合成相关酶具有更加明显的优势。
GRP78/ Bip as an inherent molecular chaperone in the endoplasmic reticulum is the marker of ER stress. GRP78/Bip作为内质网固有分子伴侣,在ER应激时表达增高,是ER应激的标记物。
It was reported that heat shock protein 90 ( HSP90), as a molecular chaperone, plays an important role in tumor development and is becoming a new target for cancer therapy. 研究发现,在体内作为分子伴侣的热休克蛋白90(Heatshockprotein90,HSP90)对肿瘤的发生发展起着重要作用,正逐渐成为肿瘤治疗的新靶点。
The protein quality control system is composed with molecular chaperone and proteolytic enzymes. 蛋白质质控系统由分子伴侣和蛋白水解酶组成[8]。
The molecular chaperone ( molecular chaperones) are a group of widespreads from bacteria to human proteins, non-covalent reconciliation with the nascent chain folding of proteins chain binding, and help them fold and transport, usually not involved in the physiological functions of target proteins. 分子伴侣(molecularchaperones)是一组从细菌到人广泛存在的蛋白质,非共价地与新生肽链和解折叠的蛋白质肽链结合,并帮助它们折叠和转运,通常不参与靶蛋白的生理功能。
Many studies showed that heat shock protein ( HSP), as a molecular chaperone, played important roles in the processing and presentation of MHC-I antigens of virus or tumors. 免疫学研究表明,热休克蛋白(HSP)作为分子伴侣(MolecularChaperone)在肿瘤及病毒抗原的MHCⅠ类限制性抗原呈递途径中发挥重要作用。